Care was taken to form groups balanced in terms of the students' educational background. This encouraged students to help one another.

All students

Ana Paula Santos Botelho Oliveira Leite

Being at this PhD Program has required intensive involvement and a lot of cooperation between the students due to our different backgrounds. The working conditions are really very good and the direction does the best to give us support. But despite the hard work and the amount of knowledge that we get along every day, I assure that we also find time to have good fun. (2005-12-01)


Presently: Research Associate at UCL Cancer Institute, London, UK.
2012 - 2014: Postdoctoral fellow at the Instituto de Medicina Molecular, Carmo Fonseca´s lab.
2006 - 2012: Ph.D. Student, Broad Institute, Aviv Regev´s Lab.
2005 - 2012: Ph.D. Program in Computational Biology, Instituto Gulbenkian de Ciência, Oeiras, Portugal.
2003 - 2006: Master Degree in Mathematical Engineering. Faculty of Sciences, University of Porto, Portugal.
1997 - 2002: Five Year Mathematics (teaching) Degree, University of Minho, Braga, Portugal.

PhD Project

Supervisor: Aviv Regev

Laboratory: Regev Lab

University: MIT


Integrative approaches for systematic reconstruction of regulatory circuits in mammals . Massachusetts Institute of Technology (2012) pp..


Ido Amit, Manuel Garber*, Nicolas Chevrier*, Ana Paula Leite*, Yoni Donner*, Thomas Eisenhaure, Mitchell Guttman, Jennifer K. Grenier, Weibo Li, Or Zuk, Lisa A. Schubert, Brian Birditt, Tal Shay, Alon Goren, Xiaolan Zhang, Zachary Smith, Raquel Deering, Rebecca C. McDonald, Moran Cabili, Bradley E. Bernstein, John L. Rinn, Alex Meissner, David E. Root, Nir Hacohen, Aviv Regev. Unbiased Reconstruction of a Mammalian Transcriptional Network Mediating Pathogen Responses. Science (2009) 326, 257 - 263.